Utilizing new ingredients, and backed by new clinical research, Natural Science has formulated a long term, 100% natural, Muscle Growth formula that is safe for both men and women, and also has many benefits for the elderly as well!
- Korean Mistletoe Extract:
Korean mistletoe (Viscum album coloratum) is a semi-parasitic plant that grows on various trees and has a diverse range of effects on biological functions, being implicated in having anti-tumor, immunostimulatory, anti-diabetic, and anti-obesity properties. It’s inclusion in Natural Muscle Growth Complex, however, is due to it’s ability to increase muscle mass and strength when combined with resistance training†. Korean Mistletoe Extract induced the mRNA expression of SREBP-1c, PGC-1α, and GLUT4, known positive regulators of muscle hypertrophy, in C2C12 cells. On the contrary, KME reduced the expression of Atrogin-1, which is directly involved in the induction of muscle atrophy†. In a 12 weeks study involving Middle Age and Elderly subjects, taking 2000mg of KME per day (the same dose found in Natural Muscle Growth Complex) exhibited a body composition that was significantly changed in the the intervention period, showing increased skeletal muscle, fat-free mass, and a decrease in body fat percent. Knee strength was measured by Cybex, demonstrating a significant effect in the KME groups compared to the placebo group† 1. Jeong J, Park CH, Kim I, et al. Korean mistletoe (Viscum album coloratum) extract regulates gene expression related to muscle atrophy and muscle hypertrophy. BMC Complement Altern Med. 2017;17(1):68. Published 2017 Jan 21. doi:10.1186/s12906-017-1575-9 2. Lim NJ, Shin JH, Kim HJ, et al. A combination of Korean mistletoe extract and resistance exercise retarded the decline in muscle mass and strength in the elderly: A randomized controlled trial. Exp Gerontol. 2017;87(Pt A):48–56. doi:10.1016/j.exger.2016.11.003
- Rehmanniae Radix Extract 20:1
Rehmanniae contains more than 140 distinct compounds that have healing effects on all kinds of diseases. The most powerful of these plant chemicals are called iridoid glycosides, which can act as powerful repair kits. These special compounds deliver a wide range of curative properties, such as anti-inflammatory, immune-modulating, antioxidant, neuroprotective, anti-aging, and regenerative actions. Two of these Iridoid Glycosides that have great effect for this formula are Catalpol and Loganin.
High levels of Catalpol leads to sharp increases† in production of EPO, VEGF, IGF1, and Beta endorphins. Increasing these anabolic and performance enhancing signals can lead to powerful increases in muscle mass, athletic performance and fat loss. Catalpol itself acts as natural performance enhancer!
A fantastic anabolic agent in its own right, Loganin is being studied currently as a treatment for skeletal muscle atrophy. In addition, Loganin seems to possess anti inflammatory, antioxidant, glucose lowering and muscle protective effects. Loganin upregulates the Atk/mTOR pathway and increases IGF1 leading to increased muscle tissue. Loganin has also been shown to increase skeletal muscle strength in animal studies and inhibits Atrogin-1 which prevents skeletal muscle atrophy. Further anabolic potential lies in its suppression of SMAD2/3 and increased expression of SMAD7†. In animals studies Loganin increased muscle mass, overall bodyweight, strength and protein synthesis making it a powerhouse anabolic! 1. Yuan XP, Liu LS, Fu Q, Wang CX. Effects of ligustrazine on ureteral obstruction-induced renal tubulointerstitial fibrosis. Phytother Res. 2012;26(5):697–703. doi:10.1002/ptr.3630
Any product is only as good as it’s absorption, and the human body has many built-in mechanism’s to prevent full absorption of certain compounds into the cells, the main protection agent is known as P-Glycoprotein Efflux. Efflux, as in the opposite of Influx, actually pumps out and away foreign agents from the cells, even when they are beneficial. To combat this, we have added in two polyphenols that have been proven to inhibit the Efflux pump†. With this addition, we can vastly increase the absorption and usage of the compounds, allowing for a massive increase in gains products that don’t contain this solution! 1. Nabekura T, Kawasaki T, Furuta M, Kaneko T, Uwai Y. Effects of Natural Polyphenols on the Expression of Drug Efflux Transporter P-Glycoprotein in Human Intestinal Cells. ACS Omega. 2018;3(2):1621–1626. doi:10.1021/acsomega.7b01679
Osthole is a bioactive coumarin derivative and has been reported to be able to enhance bone formation and improve fracture healing. Osthole enhances bone fracture healing through activation of BMP2 signaling†. Working in tandem with the BMP2 signaling is the ability to increase the muscle building natural androgens in your system†. This leads to more muscle gains, as well as the enhanced ability to repair damaged bone structures. This is combined with Hydroxy Propyl Beta Cyclodextrin, which vastly increases the ability to be absorbed into the body. 1. Wang P, Ying J, Luo C, et al. Osthole Promotes Bone Fracture Healing through Activation of BMP Signaling in Chondrocytes. Int J Biol Sci. 2017;13(8):996–1007. Published 2017 Jul 18. doi:10.7150/ijbs.19986 2. Yuan J, Xie J, Li A, Zhou F. Zhong Yao Cai. 2004;27(7):504–506.
Kaempferol, a flavonoid compound, is derived from the rhizome of Kaempferia galanga L., which is used in traditional medicine in Asia. Kaempeferol has been highly studies for its ability to prevent Estrogen deficient bone loss (osteoperosis)†. It’s inclusion in this formula is for its ability to prevent the resorption of bone material, rather increasing bone anabolism (our goal with increasing BMP signaling. Kaemperol has low oral bioavailability, so we mixed into Hydroxy Propyl Beta-CycloDextrin, allowing for far greater absorption into the body. 1. Wattel A, Kamel S, Mentaverri R, Lorget F, Prouillet C, Petit J-P, et al. Potent inhibitory effect of naturally occurring flavonoids quercetin and kaempferol on in vitro osteoclastic bone resorption. Biochem Pharmacol. 2003 Jan;65(1):35–42.
- Ligustrazine HCL
Ligustrazine (LIG) is a purified and chemically identified component of the Chinese herb Ligusticum wallichii Franchat. It is a potent blocker of vasoconstriction and has strong scavenger of oxygen free radicals. Studies have also shown a significant increase in hepatocyte growth factor and bone morphogenetic protein-7 (BMP7), allowing for both increased blood flow and nutrient distribution as well as increased BMP signaling.
All Day, All-In-One Weight Loss, Fat Reduction, Blood Sugar Control Formula
C.U.T.S. is the next generation of Glucose Disposal Agent (GDA). It is the only product with clinically validated ingredients for actual Weight Loss, Fat Reduction, and Blood Sugar support. The secret lies in the cutting edge formula, designed with specially formulated, enhanced ingredients such as GlucoVantage®, MitoBurn®, and ChromeMate®, along with high purity Gymnema and Cinnamon Extracts. These ingredients combine to change how your body metabolizes carbohydrates for energy and fat storage, stabilizing your blood sugar levels, increasing insulin sensitivity, preventing fat cells from up-taking triglycerides, and decreasing sugar/carb cravings.
C.U.T.S. is designed for anyone looking for help with WEIGHT LOSS, CONTROLLING BLOOD SUGAR levels, or increasing insulin sensitivity. Yes, C.U.T.S. along with a HEALTHY DIET can help prevent or reverse early stage Type II diabetes.
C.U.T.S. is also an excellent ‘damage control’ product for high carb cheat meals! Simply take 1-2 capsules 20 minutes before your meal and help your body re-stabilize your blood sugar levels far quicker and more efficiently than normal!
Hormonal Support for Men and Women
Optimal Hormone Peak is the first bi-daily hormone system designed to work equally well for men and women. After months of intense research, we developed a formula that accomplishes 3 goals:
- Balance Hormones: Enhances rest and recovery, helps stay in the deep sleep phase of your sleep cycle longer, increases sexual desire and orgasm ability, and slow’s down the aging process, tightening skin and reducing joint pain. With powerful adaptogens in the formula, your body will find its healthy balance again, reducing the side effects of menopause, birth control, and coming off cycle from Hormonal Therapy.
- Amplify Beneficial Hormones for enhanced muscle growth and fat loss: By naturally increasing production and release of Growth Hormone, Testosterone, and Luteinizing Hormone, your body will be primed for increased muscle growth as well as increased fat loss.
- Hormonal Detoxification: Two ingredients work in conjunction to increase the livers ability to break down excess estrogen and excrete it from the body. There are now numerous estrogen mimickers in our environment. These are wreaking havoc on our hormones, mood, and waistlines in both men and women. This excess estrogen can lead to troublesome adult acne, gynecomastia in men, breast and ovarian cancer in women, and increased fat storage in the stomach and hips.
Each PhenoSlim™ bottle contains a one month supply (120 pills). This fat loss agent has many health benefits and can be used continuously, unlike traditional stimulant based fat burners.
PhenoSlim™ is a combination of high potency ingredients, working in unison to reduce body fat and make you feel better. All the ingredients in PhenoSlim aid in fat reduction, but fat loss isn’t the only benefit. When you take PhenoSlim, your brain, cardiovascular system, and liver will all be given the nutrients they need for improved function making this the first Life Enhancing Fat Loss Agent available.
Phenoslim contains 4 active ingredients. Each ingredient provides a different pathway towards weight loss and fat reduction, and the first ingredient contains a host of health benefits as well.
- LongVida® Optimized Curcumin Extract (from Curcuma Longoma root)
LongVida®is the most bio-available form of Curcumin, it is 67-285 times more bio-available than traditional Curcumin. Curcumin itself is a powerful polyphenol, with many antioxidant properties. Daily dosage with Curcumin was shown to decrease both fat mass and body weight with no change in daily diet. This was accomplished through Curcumin’s ability to induce the browning of White Adipose tissue₁. The increase in Beige Adipose tissue (which burns lipids for energy to make heat) leads to a higher caloric output and a decrease in fat mass overall. With LongVida®’s SLCP (solid lipid Curcumin particle) technology, the Curcumin is absorbed through the lymphatic system and dispersed through your body quickly and intact. The Acid Defense capsule also protects the compound, ensuring the most potent delivery possible.
The benefits of LongVida® don’t stop there, however. LongVida®is clinically proven† to decrease inflammation, decrease liver enzymes, and increase Nitric Oxide production. These benefits lead to less joint pain and muscle soreness, and improved Nitric Oxide production is good for both hearts and vascular tissue, as well as pump enhancement during exercise. Another clinical study† showed the improvement of both cognitive function and mood.
- Factor21™ Extract (Momordica Charantia)
Factor21™ is a proprietary, 100% natural regulator of a hormone growth factor called Fibroblast Growth Factor 21 (FGF21). FGF21 is known to manage metabolism, weight loss, and glucose levels. The hormone has been linked to the burning of Brown fat and has the power to increase food satiety and decrease food intake†₂. Research on Factor21™ showed increased levels of FGF21 and changes in body weight, blood sugar levels, and insulin sensitivity.
Lactoferrin (LF) is a multifunctional protein in mammalian milk. Using a double-blind, placebo-controlled design, researchers found that participants taking 300mg per day of Lactoferrin reduced visceral abdominal fat by an astounding 12.3% in only eight weeks†₃. Decreases in body weight, BMI, and hip circumference were also shown. Lactoferrin inhibited the growth of new fat cells and promoted the breakdown of existing fat tissue. Lactoferrin increased cAMP-PKA signaling and increased overall energy expenditure. Lactoferrin also aids in the increase in Brown Adipose Tissue, as an amplifier for the powerful Bone Morphogenetic Protein 7 (BMP-7) †₄. BMP-7 is clinically proven† to reverse obesity, decrease appetite, and combat Rheumatoid Arthritis.†₅
GoGBB (Gamma-Butyrobetaine) is precursor to L-carnitine in your body. L-carnitine acts as a transport agent for converting fat to energy. However, consuming L-carnitine itself was not shown to increase cellular carnitine levels and increase carnitine excretion by nearly 40 times the normal levels†. By using the precursor Gamma-Butyrobetaine we can successfully increase carnitine levels in our body and increase metabolism and fatty acid breakdown with no nausea, odor or other common side effects of large doses of L-carnitine.
ABOUT NATURAL SCIENCE CREATION
Natural Science Creation was founded in 2010 with the idea of utilizing the highest purity compounds available with unique formulas that no other company would be willing to bring to the market. Every ingredient is lab tested for purity and compliance before being encapsulated at our GMP production facility.
With unique products and clinical doses of the key ingredients, NSC’s adaptogenic product line will allow any natural athlete to reach their goals faster, without any harmful side effects or failed drug tests.